It is one of the methods in the treatment of some dermatological diseases. It
is combination treatment which consists of psoralen and ultraviolet A (UVA).
PUVA and skin diseases:
Photochemotherapy can be used in a lot of skin problems like:
3- Atopic eczema
6- Urticaria pigmentosa
7- Chronic actinic dermatitis
8- Solar urticaria
11- Liver diseases caused itching
12- Prurigo nodularis
13- Mycosis fungoides
Side effects of PUVA (Photochemotherapy):
1- Sunburns: it can have burn after the treatment and so the dermatologist
should change the dose of UV and using moisturizers and calm lotions to
reduce the burn effect.
2- Nausea: due to using psoralen some patients have this symptom.
3- Itching: it is so common after every treatment with PUVA and with limits,
Doctors can use calm lotions for it.
4- Tanning: long time using of PUVA can cause tanning of the skin.
5- Dryness: using for long time make the skin more drier.
6- Dryness of eye if it is not protected while the treatment.
7-systemic problems to kidney and liver.
9- GIT (stomach problems with food)
10- Hepatotoxic specially with people used hepatotoxic drugs.
11-Leukoderma with long term therapy
Patients under PUVA treatment should do the following:
1- Liver function test
2- Complete blood picture
3- Renal function test
4- Eye examination
5- Skin examination for skin cancer
1- Take the psoralen dose carefully
2- Take the dose 2 hours before treatment with UV or with the supervision of
3- Avoid sun exposure after treatment
4- Take care of your eye protection
5- Using sunscreen when always go out during sunny days
6- Using calm lotions if itching
7- Wear protective eyewear